Tag Archives: biological lab

Using Machine Learning to develop blood test for key Alzheimer’s biomarker

giornata-mondiale-alzheimer-2018-824-464Alzheimer’s disease, a terminal neurodegenerative disease, has historically been diagnosed based on observing significant memory loss. Recent research has shown that a biological marker associated with the disease, a peptide called amyloid-beta, changes long before any memory-related issues are apparent.

Examining the concentration of the peptide in an individual’s spinal fluid provides an indication of risk decades before any memory related issues occur. Unfortunately, accessing spinal fluid is highly invasive, requires an anaesthetist and is expensive to conduct on large segments of the population. Hence, there is a strong effort in the research community to develop a less invasive test, such as a blood test, that can yield information about Alzheimer’s disease risk.

A recent paper by my team at IBM Research – Australia, published today in Scientific Reports, used machine learning to identify a set of proteins in blood that can predict the concentration of amyloid-beta in spinal fluid. The models we built could one day help clinicians to predict this risk with an accuracy of up to 77%.

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Scientific ReportsA blood-based signature of cerebrospinal fluid Aβ1–42 status (Published: 11 March 2019)

Roche launches two apps to increase efficiency in hospitals

ViewicsLab solutions company Roche has launched two new apps with the aim of increasing efficiency within hospitals and labs.

– The first is LabOPS, which will help labs and hospitals access their data efficiently, reduce waste and improve decisions around operations and finances.

Dx Optimization is the second app, and aims to help improve clinical effectiveness in various institutions.

The apps will be launched under Viewics, a software company acquired by Roche in 2017. The Viewics platform integrates data from a broad range of IT systems in laboratories and other healthcare settings. Roche acquired the company to provide data-driven lab business analytics for its clients, and to help improve the delivery of care.

The apps are the first to launch since the acquisition.

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